Watch Hot Ones Season 21 Episode 10 Online

John Stamos is an actor, producer, and pop-culture icon you know from shows like Full House, General Hospital, E.R., and many more. His new memoir, If You Would Have Told Me, is due out this October. But how is he with spicy food? Find out as Stamos fans out with Sean Evans and shares some of his unbelievable Hollywood stories—from friendships with comic legends like Don Rickles and Bob Saget, to memorable moments with Howard Stern and James Earl Jones.